Dose Log
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0
Taken
0
Pending
0
Skipped
Scheduled Doses
Modifiers
High-fat breakfast with morning dose
Delays Tmax +2hr, Cmax −21% (Yao et al. 2016)
High-protein meal near any dose
BBB amino acid competition → ~20% CNS reduction
Poor sleep / high stress
Raises effective thresholds ~120 ng/mL
PK profile
24-Hour LD Plasma Concentration — from today's log
Peak LD
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ng/mL
Min Trough
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ng/mL
Time <810
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hrs/day
Time >2800
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hrs/day
Scheduled Rytary
Rescue doses
Therapeutic ≥810
High risk ≥2800
Confirmed dose
Projected dose
PK model: Bateman 1-compartment. Rytary tri-phasic ka (IR=3.2, ER1=0.55, ER2=0.18 hr⁻¹, fractions 27/48/25%). PD correction +38% Cmax (FDA NDA 203312). Food effect: Yao et al. 2016. Steady-state Day 3. Unconfirmed doses shown at default times/compositions. Semi-quantitative — not a substitute for clinical judgment. Intrasubject variability ±20%.
Rescue / PRN
Today's Log — Chronological
No doses logged yet today.
Confirm Dose
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